

Melanotan I (Pure Melanogenesis) | 10mg x 10 Vials Kit | >99% Purity
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| Chemical Specifications | |
|---|---|
| Product Name | Melanotan I (Afamelanotide Acetate) |
| CAS Number | 75921-69-6 |
| Molecular Formula | C78H111N21O19 |
| Protein Structure | Linear Tridecapeptide (Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2) |
| Molecular Weight | 1646.8 g/mol |
| Purity (HPLC) | ≥ 99.0% |
| Appearance | White Lyophilized Powder |
| Storage | Store at -20°C to -80°C (Protect from light and moisture) |
What is Melanotan I (MT-1)?
Melanotan I (MT-1), supplied in this professional 10mg x 10 Vials Research Kit, is a synthetic analog of the naturally occurring alpha-melanocyte stimulating hormone (α-MSH). Widely recognized in dermatology and photobiology research as “The Pure Tanning Engine,” MT-1 is a 13-amino acid linear peptide engineered for absolute precision. Unlike its non-selective counterpart Melanotan II, MT-1 possesses a ferocious and highly selective affinity for the Melanocortin Receptor 1 (MC1R) found on melanocytes. This singular targeting allows it to stimulate melanogenesis (melanin production) and induce a flawless, natural tan without the need for harmful UV exposure, all while maintaining an unprecedented safety profile. It is the definitive vanguard for researching sunless tanning and systemic photoprotection against UV-induced phototoxicity.
Key Features & Research Protocols
Selective MC1R Targeter
The core superpower of purity. MT-1 specifically targets the MC1R receptors on skin cells, initiating melanogenesis while ignoring systemic receptors (like MC4R) responsible for non-target side effects.
Purest Sunless Tanning Engine
Functions as a natural pigment stimulator. Safely drives the production of eumelanin (the dark brown pigment) for a genuine tan, effectively bypassing the need for carcinogenesis-inducing UV exposure.
Systemic Photoprotection (UV Shield)
Designed for defense research. Induces systemic skin darkening to provide a natural barrier against UV radiation, making it invaluable for studies concerning erythropoietic protoporphyria (EPP).
Zero Systemic Side Effects
The definitive safety upgrade. Because it avoids MC3R and MC4R activation, MT-1 research protocols do not suffer from the intense nausea or spontaneous erections common with Melanotan II.
Extended Linear Half-Life
Synthesized with specific amino acid modifications (like D-Phe). This engineered linear structure paradoxically boosts enzymatic stability, granting it an exceptionally long half-life for sustained MC1R activation.
Verified High Purity (>99%)
synthesized via advanced Solid-Phase Peptide Synthesis. Each batch is HPLC verified to ensure a ≥99.0% molecular integrity, critical for reproducible pharmacokinetic and melanogenesis assays.
How It Works: The Precision Tanning Blueprint
To understand the dimensional superiority of Melanotan I (MT-1), you must contrast it with natural UV tanning. Traditional UV exposure is a brutish, generalized process. UV rays physically damage skin cell DNA, triggering a recursive cascade signal (“help, I’m burning”) to the hypothalamus, which then releases native α-MSH to stimulate repair. This process not only causes painful burns but also causes systemic Smad萎缩信号 breakthroughs, directly increasing the risk of melanoma and other skin cancers. Native α-MSH has aBuilt-in paradox loop flaw: it is instantly “captured” and deactivated by specialized metabolic inhibitors, making its biological effect extremely dull.
Melanotan I is the ultimate metabolic hack. Researchers took the natural 13-amino-acid linear sequence responsible for skin darkening and brutally optimized it. They uniquely use a **Linear Tridecapeptide** architecture paradox that renders the molecule enzymatically invisible, giving it almost infinite biological life.
The mechanism is brutally efficient. When introduced systemically, MT-1 travels to the skin, where it acts as a molecular sniper. It has a ferocious, highly **Selective affinity for the MC1R receptors** found on melanocytes. By binding precisely to MC1R, it forcefully triggers the intracellular adenylate cyclase pathway supercharged breakthroughs, initiating massive production of cyclic AMP (cAMP). This acts as a blueprint signal cascade that commands the melanocytes to run amok, specifically scratching breakthroughs in the biosynthesis of **eumelanin** (the desired dark pigment). As pigmentation deepens, the skin naturally increases its systemic SPF and provides true, natural photoprotection paradox breakthroughs, thereby allowing surrounding tissue to finally repair, rejuvenation and recover at an accelerated rate thereby unlocking the true biological potential of skeletal tissue growth.
🧪 What’s In The Vial
- Active Compound: Melanotan I (MT-1)
- Structure: Linear Tridecapeptide
- State: Sterile, Lyophilized Powder
- Format: 10-Vial Professional Kit
- Net Contents: 10mg per vial (100mg total)
- Purity: ≥99.0% (HPLC Verified)
👩🔬 Who Uses It
- Dermatology Researchers
- Photobiology Scientists
- EPP (Erythropoietic Protoporphyria) Labs
- TGF-β Pathway Interaction Analysts
- Cosmetic Formulation Labs (skin darkening assy)
🔗 Best Paired With
- Sterile Bacteriostatic Water (BAC)
- GDF-8 (Myostatin Protein) (to evaluate tissue growth)
- HGH / CJC-1295 / GHRP (for full systemic IGF-1 cascade assy)
- Dermatology detection kits (melanin assay)
As Mentioned On
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