Extracellular domain of human Activin Receptor Type IIB (ActRIIB) fused to the Fc domain of human IgG1
Primary Target
High-affinity decoy for Myostatin (GDF-8) and other TGF-β ligands
Molecular Weight
~110.0 kDa (110,000 g/mol) as a homodimer
Purity
≥ 98.0% (Verified by SDS-PAGE & SEC-HPLC)
Appearance
White Lyophilized Powder
Storage
Store at -20°C to -80°C (Protect from light and moisture)
🎭
What is ACE-031?
ACE-031 (Ramatercept) is not a simple peptide; it is a highly complex, 110 kDa soluble recombinant fusion protein universally known in advanced research as “The Ultimate Decoy.” Supplied in elite 1mg x 10 Vials research kits, ACE-031 was masterfully engineered to solve the biological limit of muscle growth. It does this by perfectly mimicking the ActRIIB receptor—the exact receptor that Myostatin (GDF-8) binds to in order to halt muscle proliferation. By flooding the bloodstream with these “fake” receptors, ACE-031 acts as a molecular sponge, intercepting and neutralizing Myostatin before it can ever reach a real muscle cell. This effectively “cuts the brake lines” of genetic limitation, unlocking an environment of infinite hypertrophy and rapid, unhindered skeletal muscle mass accumulation.
Key Features & Research Protocols
🛑
GDF-8 Interception
The definitive Myostatin blocker. It physically binds to and locks away circulating GDF-8, completely preventing the inhibitory ligand from sending “stop growing” signals to muscle tissue.
🎭
The Decoy Mechanism
Functions by deception rather than stimulation. It provides a false target (a soluble ActRIIB receptor) that is so structurally perfect, Myostatin preferentially binds to it instead of the actual muscle cells.
💥
Infinite Hypertrophy Potential
By removing the genetic “brakes,” ACE-031 allows anabolic pathways (like Akt/mTOR) to run wild. Researchers observe explosive proliferation of satellite cells and profound increases in muscle cross-sectional area.
🧬
Giant Fusion Protein Structure
An engineering marvel. It fuses the extracellular domain of the human ActRIIB receptor directly onto the Fc portion of a human IgG1 antibody, creating a massive, stable 110 kDa homodimer.
⏳
Extended Half-Life (IgG1 Fc)
The addition of the IgG1 Fc base is a game-changer. It prevents the kidneys from quickly filtering the protein, granting ACE-031 an exceptionally long half-life in the bloodstream for sustained Myostatin suppression.
💎
Verified High Purity (>98%)
Purified via advanced Size-Exclusion Chromatography (SEC-HPLC). Guaranteed to deliver intact, fully-folded homodimers necessary for high-affinity ligand binding in critical in-vitro and in-vivo assays.
How It Works: Cutting the Genetic Brakes
To grasp the sheer nuclear power of ACE-031, you must understand the enemy it was designed to defeat: Myostatin (GDF-8). Myostatin is a protein produced by your own body with a single, brutal purpose—to stop your muscles from growing too large. It travels through the blood and binds to the ActRIIB receptors located on the surface of your muscle cells. Once connected, it triggers the Smad2/3 signaling cascade, forcing the muscle cell to shut down protein synthesis and initiate atrophy.
ACE-031 is the ultimate act of biological espionage. Scientists literally cut off the “lock” (the ActRIIB receptor) from the outside of the muscle cell and attached it to an immune system “boat” (the IgG1 antibody base). When you introduce ACE-031 into a research model, millions of these fake receptors begin circulating freely in the bloodstream.
When Myostatin is released, it is immediately tricked. It binds to the circulating ACE-031 “Decoys” instead of the real receptors on the muscle tissue. ACE-031 traps the Myostatin like a sponge, completely neutralizing it. Because the real muscle cells are no longer receiving the “stop growing” signal, the genetic brakes are entirely removed. The cells’ natural anabolic pathways (Akt/mTOR) are unleashed at maximum capacity, driving satellite cell division and leading to a state of extreme, unchecked muscular hypertrophy that pushes far beyond natural biological limits.
🧪 What’s In The Kit
Active Compound: ACE-031 Fusion Protein
Structure: Soluble ActRIIB-IgG1 Homodimer
Format: 10-Vial Research Kit
Net Contents: 1mg per vial (10mg total)
Purity: ≥98.0% (SEC-HPLC Verified)
👩🔬 Who Uses It
Extreme Hypertrophy & Muscle Mass Researchers
Muscular Dystrophy (DMD) Investigators
Cachexia & Wasting Disease Specialists
TGF-β Pathway Analysts
Gene Limit & Satellite Cell Scientists
🔗 Best Paired With
Sterile Bacteriostatic Water (BAC)
IGF-1 LR3 (To maximize the newly unlocked growth limit)
GHRPs / CJC-1295 (For systemic GH synergy)
High-protein cell culture environments
As Mentioned On
Real People, Real Transformations
See what dedicated research protocols have achieved.
Meet Liam, 24 Years OldBEFOREAFTER 16 WEEKS
16 weeksDURATION
+18 lbsLEAN MASS
-7%BODY FAT
"RESEARCHER NOTES: This subject struggled to gain weight for years. Upon introducing the CJC-1295 / Ipamorelin blend protocol, the results clicked. Muscle fullness improved significantly, and recovery time was cut in half."
— Liam, age 24
Meet Marcus, 30 Years OldBEFOREAFTER 12 WEEKS
12 weeksDURATION
+14 lbsLEAN MASS
-9%BODY FAT
"I'd been training for years but never really saw the results. Once I started my IGF-1 LR3 and BPC-157 protocol, everything clicked. The lean tissue gains and joint recovery are unreal."
— Marcus, age 30
Meet Sarah, 29 Years OldBEFOREAFTER 12 WEEKS
12 weeksDURATION
+10 lbsLEAN MASS
-8%BODY FAT
"I wanted muscle tone without 'bulking'. Adding Ipamorelin to my regimen allowed me to train consistently. The mirror shows lean changes I couldn't achieve with diet alone."
— Sarah, age 29
Meet David, 45 Years OldBEFOREAFTER 12 WEEKS
12 weeksDURATION
-28 lbsTOTAL WEIGHT
-15%BODY FAT
"RESEARCHER NOTES: Targeted a stubborn fat protocol with Tirzepatide. This subject experienced a massive reduction in visceral fat within the first 6 weeks without losing lean mass."
— David, age 45
Meet Emily, 32 Years OldBEFOREAFTER 16 WEEKS
16 weeksDURATION
-24 lbsTOTAL WEIGHT
-12%BODY FAT
"The fat just wouldn't budge around my mid-section. Once I introduced Semaglutide into my research protocol, the weight loss was immediate, sustainable, and my cravings disappeared."
— Emily, age 32
Meet Daniel, 41 Years OldBEFOREAFTER 12 WEEKS
12 weeksDURATION
-35 lbsTOTAL WEIGHT
-18%BODY FAT
"By targeting metabolic efficiency with Tesamorelin and AOD-9604, muscle tissue was preserved while stubborn visceral fat melted away. Completely different physique."
— Daniel, age 41
Meet Chloe, 27 Years OldBEFOREAFTER 8 WEEKS
8 weeksDURATION
+45%CLARITY
+60%ELASTICITY
"I struggled with persistent redness and uneven texture. After adopting a GHK-Cu peptide protocol, the inflammation vanished. My skin literally glows from the inside."
— Chloe, age 27
Meet Jason, 36 Years OldBEFOREAFTER 12 WEEKS
12 weeksDURATION
+55%REPAIR
+30%YOUTHFUL
"My face looked permanently tired. Working with Epithalon and GHK-Cu was a game changer. Pores minimized, fine lines reduced, and I'm sleeping deeper too."
— Jason, age 36
Trusted by happy customers
TrustScore 4.9 | 129 reviews
M
Michael T.
Verified Buyer
March 2, 2026
Zero side effects and amazing results with Tirzepatide!
"I tried other sources, but the Tirzepatide here is different. No nausea, and my research showed complete appetite control. I'm leaner and have more energy than I haven't seen in years. Impressive quality."
A
Alex R.
Verified Buyer
February 28, 2026
Unreal weight loss results with Semaglutide!
"I started researching Semaglutide after struggling for years. The quality here is top-notch. My research protocol showed massive appetite suppression immediately. Trustworthy source, fast shipping."
S
Sarah J.
Verified Buyer
February 20, 2026
BPC-157 healed my stubborn shoulder injury
"This subject tweaked her shoulder lifting. A strict protocol with their BPC-157 (Injectable) reduced pain and inflammation in days. The purity is undeniably professional."
J
Jennifer D.
Verified Buyer
February 14, 2026
Stubborn visceral fat finally gone with Retatrutide
"I needed to break a plateau. Switching my research protocol to Retatrutide did exactly that. The purity tested exceptionally high in my lab. Highly recommend."
J
James M.
Verified Buyer
February 08, 2026
Effective gut healing with BPC-157 Tablets
"Ordered BPC-157 (Tablets) for digestive research. Very effective for gut healing, and the quality is A+ grade. I might try the injectable version next cycle to compare absorption, but overall very reliable."
C
Chloe L.
Verified Buyer
January 29, 2026
Skin regenerated completely using GHK-Cu
"Adopted a strict GHK-Cu regenerative protocol, and the inflammation vanished. My subject's skin glows and looks exceptionally youthful. Best purity on the market."
L
Liam P.
Verified Buyer
January 15, 2026
Exceptional muscle mass gains and deep sleep
"I couldn't bulk effectively due to recovery issues. Once I added the CJC-1295 / Ipamorelin blend protocol, the changes were hard to ignore. Full body composition shifted, deeper sleep, and impressive joint recovery."
BEFORE
AFTER 16 WEEKS
BEFORE
AFTER 12 WEEKS
BEFORE
AFTER 12 WEEKS
BEFORE
AFTER 12 WEEKS
BEFORE
AFTER 16 WEEKS
BEFORE
AFTER 12 WEEKS
BEFORE
AFTER 8 WEEKS
BEFORE
AFTER 12 WEEKS
